The structure–energy landscape of NMDA receptor gating
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چکیده
منابع مشابه
The structure-energy landscape of NMDA Receptor gating
N-Methyl-D-aspartate (NMDA) receptors are the main calcium-permeable excitatory receptors in the mammalian central nervous system. The NMDA receptor gating is complex, exhibiting multiple closed, open, and desensitized states; however, central questions regarding the conformations and energetics of the transmembrane domains as they relate to the gating states are still unanswered. Here, using s...
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2017
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio.2487